Behaviour: Loving mothers ease stress through epigenetics
نویسندگان
چکیده
منابع مشابه
Epigenetics, Behaviour, and Health
: The long-term effects of behaviour and environmental exposures, particularly during childhood, on health outcomes are well documented. Particularly thought provoking is the notion that exposures to different social environments have a long-lasting impact on human physical health. However, the mechanisms mediating the effects of the environment are still unclear. In the last decade, the main f...
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For the first time, a complex behavior, mothers caring for their offspring, has been linked to a semimysterious repeating amino acid sequence common to mammals. These repeats, found more often in mammals than other vertebrates, have been seen in the past to affect protein–protein interactions, transcriptional regulation, and phenotypic variation. Japanese biologists Shintaroh Ueda, Den’etsu Sut...
متن کاملEpigenetics, brain evolution and behaviour.
Molecular modifications to the structure of histone proteins and DNA (chromatin) play a significant role in regulating the transcription of genes without altering their nucleotide sequence. Certain epigenetic modifications to DNA are heritable in the form of genomic imprinting, whereby subsets of genes are silenced according to parent-of-origin. This form of gene regulation is primarily under m...
متن کاملStress, Epigenetics, and Alcoholism
Acute and chronic stressors have been associated with alterations in mood and increased anxiety that may eventually result in the development of stress-related psychiatric disorders. Stress and associated disorders, including anxiety, are key factors in the development of alcoholism because alcohol consumption can temporarily reduce the drinker's dysphoria. One molecule that may help mediate th...
متن کاملMaternal Behaviour during Develop- Undoing Epigenetics
ment can have a powerful influence on stress levels of the offspring later in life as a result of lasting epigenetic modifications. According to work published in The Joural of Neuroscience, it now seems that just as gene expression can be altered during development, it can also be altered later in life to reverse these modifications. Stress responses are mediated by regulation of the hypothala...
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ژورنال
عنوان ژورنال: Nature Reviews Neuroscience
سال: 2004
ISSN: 1471-003X,1471-0048
DOI: 10.1038/nrn1483